What Are Polynucleotides? The Regenerative Skin Treatment You Need to Know About
Polynucleotides are fast becoming one of the most talked-about treatments in advanced aesthetics, and for good reason. With their powerful ability to regenerate and repair skin, this injectable treatment is ideal for those seeking subtle, natural-looking results that restore skin health from within.
At The Lili Skin Clinic in Beckington, Frome, just outside Bath, we’re proud to offer this cutting-edge treatment, performed exclusively by experienced NHS GP and aesthetic doctor, Dr Kate.
In this article, we’ll explore what polynucleotides are, how they work, who they’re for, and what results you can expect.
🌟 What Are Polynucleotides?
Polynucleotides are biostimulating injectable treatments derived from purified fragments of DNA (often sourced from salmon). Don’t worry – they’re safe, sterile, and highly compatible with the human body.
Rather than adding volume like fillers or freezing muscles like anti-wrinkle injections, polynucleotides stimulate the body’s own collagen, elastin, and cellular repair systems, working deep within the skin to:
Boost hydration
Improve skin elasticity
Reduce inflammation
Support tissue regeneration
Enhance skin tone and texture
In short, they help the skin heal and renew itself at a cellular level.
What Skin Concerns Do Polynucleotides Treat?
Polynucleotides are incredibly versatile and can be used to treat a range of concerns, including:
Fine lines and early signs of ageing
Dull, dehydrated, or thinning skin
Acne scarring and post-inflammatory pigmentation
Under-eye circles and crepey texture
Redness, inflammation, or sensitivity
Sun-damaged or environmentally stressed skin
They’re especially effective in delicate areas that are traditionally hard to treat – like the under-eyes, neck, and décolleté.
Who Are Polynucleotides For?
At The Lili Skin Clinic, we recommend polynucleotides for anyone looking to:
Improve overall skin quality
Support long-term skin health
Regenerate tired or damaged skin
Enhance results from other treatments (e.g. microneedling, Profhilo)
They’re suitable for most skin types and all genders, particularly those looking for non-volumising, regenerative treatments.
What Is the Treatment Process Like?
A full course usually consists of 3 sessions spaced 2–4 weeks apart, depending on your skin’s needs.
Here’s what to expect:
Treatment takes 20–30 minutes
Minimal discomfort with small, targeted injections
Little to no downtime – you can return to daily life straight away. The small bumps tend to take 48 hours to settle so some people rather not be back at work or if you have an event that day depending how concerned you are on others noticing.
Results start to develop within 2–4 weeks and continue to improve over time
You may be advised to repeat the treatment every 6–9 months to maintain results.
Why Choose The Lili Skin Clinic?
Located in Beckington near Frome and Bath, The Lili Skin Clinic offers doctor-led aesthetic care in a safe, private setting.
Every treatment is carried out by Dr Kate, a fully qualified NHS GP with 14+ years of medical experience and advanced aesthetic training. Her holistic, patient-first approach ensures that your results are natural, ethical, and always in line with your overall wellbeing.
📍 Book Your Polynucleotide Consultation in Somerset
Ready to discover what this regenerative treatment can do for your skin?
📩 Get in touch to book your personal consultation with Dr Kate, or send us a message to learn more about whether polynucleotides are right for you.